Risk factors of Atopic dermatitis in 1- to 4-Years Old Children in Al-Bayda city, Libya

• Marfoua. S. Ali

  Zoology Department

  Author

• Samia M Efkeren

  Zoology Department, Faculty of Science, Omar Al-Mukhtar University, Al-Bayda, Libya

  Author

• Salema R.M Qowaider

  Microbiology and Immunology Department, Faculty of Medicine,, Omar Al-Mukhtar University, Al-Bayda, Libya

  Author

• Salma. A. Bianco

  Razi Med Lab- El-Bayda, Libya

  Author

may be an important factor in children with atopic eczema under 4 years. Our objective was to assess the extent and characteristics of confirmed and unconfirmed diagnoses of AD in 112 children who were diagnosed by Pediatric Allergy Clinic at El-Beyda’s hospital with a high possibility of having AD at some point in their lifetimes. Sera from the patients were analyzed for specific IgE antibodies to 20 allergens. About 95% of children with AD have IgE-mediated clinical reactivity. The prevalence of positive cases with food allergens ranged from 19-20%, and environmental factors ranged from 11-14% for boys and girls respectively.  Positive cases of environmental factors in this population were recorded against some species of plants. As a result, a combined sensitization to food and environmental allergens not only has an additive increase in serum IgE antibody production, but also increases the risk of developing allergic diseases such as asthma during childhood. An evaluation for AD should be considered to these children.

Ali, M.S. Mekal, F.H. Taib, R. M. and Qowaider, S. R. (2016). Prevalence and risk factors of childhood Asthma in El-Beyda city in Northeast of Libya. Journal of Pharmacy and Biological Sciences 11 (5): 115-118.

Bieber, T. (2010). ATOPIC dermatitis. Annals of Dermatology 22(2): 125-137.

Brenninkmeijer, E. Schram, M. Leeflang, M. Bos, J. and Spuls, P. I. (2008). Diagnostic criteria for atopic dermatitis: a systematic review. British Journal of Dermatology 158: 754-765.

Breuer, K. Heratizadeh, A. Wulf, A. Baumann, U. Constien, A. Tetau, D. Kapp, A. and Werfel, T. (2004). Late eczematous reactions to food in children with atopic dermatitis. Clinical & Experimental Allergy 34: 817-824.

Chiu, C.-Y. Huang, Y.-L. Tsai, M.-H. Tu, Y.-L. Hua, M.-C. Yao, T.-C. Yeh, K.-W. and Huang, J.-L. (2014). Sensitization to food and inhalant allergens in relation to atopic diseases in early childhood: a birth cohort study. PloS one, 9: e102809.

Deleuran, M. and Vestergaard, C. (2014). Clinical heterogeneity and differential diagnosis of atopic dermatitis. British Journal of Dermatology 170: 2-6.

Eigenmann, P. A. Sicherer, S. H. Borkowski, T. A. Cohen, B. A. and Sampson, H. A. (1998). Prevalence of IgE-mediated food allergy among children with atopic dermatitis. Pediatrics 101: e8-e8.

Elfaituri, S. S. (2015). Pediatric dermatoses in Benghazi, Libya. Indian Journal of Paediatric Dermatology 16: 64.

Galli, S. J. and Tsai, M. (2012). IgE and mast cells in allergic disease. Nature medicine 18: 693-704.

Greenhawt, M. (2010).The role of food allergy in atopic dermatitis. Allergy and asthma proceedings,. OceanSide Publications, Inc, 392-397.

Kulig, M. Bergmann, R. Tacke, U. Wahn, U. and Guggenmoos‐Holzmann, I. (1998) .Long‐lasting sensitization to food during the first two years precedes allergic airway disease. Pediatric allergy and immunology 9: 61-67.

Larsen, F. S. (1996). Atopic dermatitis: an increasing problem. Pediatric Allergy and Immunology 7: 51-53.

Lee, J. H. Suh, J. Kim, E. H. Cho, J. B. Park, H. Y. Kim, J. Ahn, K. Cheong, H. K. and Lee, S.-I. (2012). Surveillance of home environment in children with atopic dermatitis: a questionnaire survey. Asia Pacific Allergy 2: 59.

Maloney, J. M. Rudengren, M. Ahlstedt, S. Bock, S. and Sampson, H. A. (2008). The use of serum-specific IgE measurements for the diagnosis of peanut, tree nut, and seed allergy. Journal of Allergy and Clinical Immunology 122: 145-151.

Mcnally, N. Williams, H. and Phillips, D. R. (2001). Atopic eczema and the home environment. British Journal of Dermatology 145: 730-736.

Mcnally, N. J. Phillips, D. R. and Williams, H. C. (1998). The problem of atopic eczema: aetiological clues from the environment and lifestyles. Social Science & Medicine 46: 729-741.

Oranje, A. and De Waard-Van Der Spek, F. (2000). Atopic dermatitis and diet. Journal of the European Academy of Dermatology and Venereology 14: 437-438.

Schäfer, T. Stieger, B. Polzius, R. and Krauspe, A. (2008). Atopic eczema and indoor climate: results from the children from Lübeck allergy and environment study (KLAUS). Allergy 63: 244-246.

Schloss, O.M. (1915). Allergy to common foods. Transactions of the American Ophthalmological Society 27:62-68.

Suh, K.Y. (2010).Food allergy and atopic dermatitis: separating fact from fiction. Seminars in cutaneous medicine and surgery, Frontline Medical Communications 72-78.

Tariq, S. M. Matthews, S. M. Hakim, E. A. and Arshad, S. H. (2000). Egg allergy in infancy predicts respiratory allergic disease by 4 years of age. Pediatric Allergy and Immunology 11: 162-167.

Wassmann, A. and Werfel, T. (2015). Atopic eczema and food allergy. Food Allergy: Molecular Basis and Clinical Practice. Karger Publishers.

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