The effect of HCG, 17Beta-Estradiol and hydrocortisone in some blood parameters in female rabbits

• Safi Taher Al - Mahmoud Al - Mahmoud

  Author

• Salah Salim

  Author

The resent study was experimental research conducted in High Health institute in Egdabia .it was aimed to study the effect of estrdiolB-17, HCG and hydrocortisone on blood parameters. local rabbits (20) caged as experimental animal, divided into four groups, 1 st group (5) rabbits used as control. 2 nd group(5)rabbits injected 30 iu/kg s/c HCG Human chorionic gonadotropin, 3ld group(5)rabbits injected 0.1 mg/kg i.m 17 beta- estradiol, the 4th group(5)rabbits injected 0.1 mg/kg s/c hydrocortisone , After five weeks blood serum tested for cholesterol ,LDL- low density lipoprotien ,HDL- High density lipoprotien, TG(triglycerides), Total protein and blood pH, body weigh also have been taken before treatment and used to study the effect of studied hormones . The study show that 17 Beta-estradiol decreased the level of cholesterol (-47.53%),HDL(- 33.33%), TG(-43.34) , and increased the level of LDL(22.24%),glucose(17.58%) and Total protein (20.13%) with no significant effects on body weight and pH.the level of HDL(-35.48%) ,total protein (-18.90%) and body weight (-14.88).blood pH was not altered . Hydrocortisone changed the blood parameters and increased the level of LDL (58.35%), TG (12.35) and glucose (26.34%) and decreased the cholesterol (-14.98%) and Total protein (-12.3%) with no effect on blood pH and body weight. The important of the present study show the alteration in blood parameters may cause available effects on body physiological function and become risk factors and must be tested before using the hormone for treatments.HCG raised the level of Cholesterol (49.25%) ,LDL(92.5%),TG(120.75%) and glucose(!8.78%) and lowered

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