Clinical manifestations of gastro esophageal reflux among patients with chronic laryngitis in Benghazi, 2018
- Authors
-
-
Yosef Hassan. S. Abdulkarim
Otolaryngology medical col-lage Benghazi university, ENT department, Benghazi medical centerAuthor -
Hajer M. M Farkash
Otolaryngology medical col-lage Benghazi university, ENT department, Benghazi medical centerAuthor -
Khaled G Hasen
Otolaryngology department, medical college, Al-Mukhtar university, ENT department, Albeda HospitalAuthor
-
- Keywords:
- Gastroesophageal reflux disease, chronic laryngitis, hoarseness of voice
- Abstract
-
Gastroesophageal reflux disease is a chronic, complex condition that may present with atypical symptoms, including laryngitis. The aim of study to demonstrates the relationship of sings of reflux laryngitis in patients with typical manifestations of Gastroesophageal reflux disease (GERD). The present study included a total of 60 patients suffering chronic laryngitis with a range of age of 23 to 88 years in descriptive study in Benghazi Medical Center in the year 2018. History was collected and indirect laryngoscopy done for cases and data were analyzed using SPSS 23.0. Results The most common symptoms were hoarseness of voice, throat clearing, dysphagia, throat discomfort and globus sensation. No significant association of symptoms with gender of the patients. Most common laryngeal findings were hyperemia, vocal cord changes and posterior commisure hypertrophy. Significant association included only posterior commissure hypertrophy and infra-glottal edema. Conclusions and recommendations, Many didn't seek medical advice and most had no diagnostic procedure. Stronger study designs using proper diagnostic technique and patient education with staff training are recommended.
- Downloads
-
Download data is not yet available.
- References
-
Alharethy S, Baqays A, Mesallam T, Syouri F, Al Wedami M, Aldrees T, and AlQabbani A. (2018). Correlation between Allergic Rhinitis and LaryngopharyngealReflux BioMed ResearchInternational https://doi.org/10.1155/2018/2951928.
Cobzeanu MD, Voineag M,Drug VL,Ciubotaru A,Cobzeanu BM, Palade OD.(2012). Laryngeal morphological changes due to gastroesophageal reflux disease. Rev Med Chir Soc Med Nat Iasi. 116(4), pp.1011-1015.
De Bortoli N, Nacci A, Savarino E, Martinucci I, Bellini M, Fattori B, Ceccarelli L, Costa F, Mumolo MG, Ricchiuti A, Savarino V, Berrettini S and Marchi S. (2012). How many cases of laryngopharyngeal reflux suspected by laryngoscopy are gastroesophageal reflux disease-related? World J Gastroenterology 18(32), pp. 4363-4370.
Dilen da Silva C, Niedermeier B and Portinho F. (2015). Reflux Laryngitis: Correlation between the Symptoms Findings and Indirect Laryngoscopy. Int Arch Otorhinolaryngol. 19, pp. 234–237.
Dymek A, Dymek L, Starczewska-Dymek L, Bożek A, Dymek T and Nowak K. (2012). Laryngopharyngeal Reflux (LPR) in patients with persistent hoarseness. Otolaryngol Pol. 66(1), pp. 33-8.
El-Serag HB, Sweet S, Winchester CC, Dent J. (2013). Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut. 63(6), pp. 871–880. doi:10.1136/gutjnl-2012-304269.
Heidelbaugh J, Gill A, Harrison R, and Nostrant T. (2008). Atypical Presentations of Gastroesophageal Reflux Disease. Am Fam Physician. 78(4), pp. 483-488.
Koufman J. (1991). The otolaryngologic manifestations of gastroesophageal reflux disease (GERD): A clinical investigation of 225 patients using ambulatory 24-hour ph monitoring and an experimental investigation of the role of acid and pepsin in the development of laryngeal injury, The Laryngoscope. vol. 101, pp. 1–78.
Koufman, J, Aviv J, Casiano R, and Shaw G. (2002). Laryngopharyngeal reflux: a position statement of the committee on speech, voice, and swallowing disorders of the American Academy of Otolaryngology-head and neck surgery. Otolaryngology-Head and Neck Surgery, vol. 127, pp. 32– 35.
Parsons P. and Mastronarde G. (2010). Gastroesophageal reflux disease and asthma, Current opinion in pulmonary medicine, vol.16, no 1, pp 60-63.
Pribuisiene R, Uloza V,andJonaitis L. (2002). Typical and atypical symptoms of laryngopharyngeal reflux disease. Medicina (Kaunas), vol. 38 (7), pp. 699–705.
Reiter R, Hoffmann TK, Pickhard A, Brosch S (2015). Hoarseness—causes and treatments. Dtsch Arztebl Int 112, pp. 329–337.
Yazici Z, Sayin I, Kayhan F, and Biskin S. (2010). Laryngopharyngeal reflux might play a role on chronic nonspecific pharyngitis, European Archives of Oto-Rhino- Laryngology. 267 (4), pp. 571–574.
Yuksel ES and Vaezi MF. (2012). New Developments in Extraesophageal Reflux Disease Gastroenterology & Hepatology.8(9), pp.256-261.
- Downloads
- Published
- 2025-09-18
- Issue
- Vol. 39 No. 1 (2024)
- Section
- Articles
- License
-
Copyright (c) 2024 Yosef Hassan. S. Abdulkarim, Hajer M. M Farkash, Khaled G Hasen (Author)

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Copyright of the articles Published by Almukhtar Journal of Science (MJSc) is retained by the author(s), who grant MJSc a license to publish the article. Authors also grant any third party the right to use the article freely as long as its integrity is maintained and its original authors and cite MJSc as the original publisher. Also, they accept the article remains published by the MJSc website (except in the occasion of a retraction of the article).
How to Cite
Similar Articles
- Mariam M. Madany, Amenh B. Yousif, Rasmia H. Feituri, Naemia Gawbaa, Amal Khazmi, Surgical Outcomes of Congenital Heart Disease in the Eastern Region of Libya , Al-Mukhtar Journal of Sciences: Vol. 39 No. 2 (2024)
- Kaula. A. Saad, Hanan. A. Ageehal, Ahmed. S. Elgrari, An Epidemiological Study of Cutaneous Leishmaniasis in the Cities of Sirte and Jadu, Libya: During 2019-2020 , Al-Mukhtar Journal of Sciences: Vol. 40 No. 1 (2025)
- Manal H. Algraiw, Huda H . Algriw, Omar I. Abusnena, Combatting Fatigue and Bone Pain: The Impact of Vitamin D Treatment in the General Practice Setting , Al-Mukhtar Journal of Sciences: Vol. 40 No. 1 (2025)
- Aeshah A. Altayf, The Level of 25-Hydroxy Vitamin D3 in Gingival Crevicular fluid and Serum Pre-Post Scaling and Root Planning in Chronic Periodontitis Patients in Western Libya: Comparative Study , Al-Mukhtar Journal of Sciences: Vol. 38 No. 4 (2023)
- Mabrouka A. Bofarraj, Faiza M. Ali, Hameeda F. Essay, Reema S. Salem, Rania .M. Altaib, Fatema. I. Mahmoud, Prevalence of Congenital Heart Disease Among Preterm Newborns Between 28 and 35 Weeks Admitted at Al Bayda Medical Center, Libya (2021) , Al-Mukhtar Journal of Sciences: Vol. 39 No. 1 (2024)
- Hanan Mukassby , Hala A. Ammar, Salma M. Salem, Najat El-Rugige. , Hana Saeid Abdulali,, Rasmia H. Feituri, The Types of Congenital Heart Disease in Down Syndrome Patients: Single-center Review of Cases in Benghazi, Libya , Al-Mukhtar Journal of Sciences: Vol. 39 No. 3 (2024)
- Raul I. Gambalan, Janette L. Calo, Jerlinda P. Roa, Salih A. S. Alsalimi, Compliance of Hand Hygiene Among Health Care Professionals and Allied Health Workers in the Prevention of Bacterial Contamination , Al-Mukhtar Journal of Sciences: Vol. 38 No. 4 (2023)
- Khaled Faiz, Jamal Gomati, Tariq Elhoony, Tariq Aldarat, Salah Eltaktouk, Muftah Elkhafifi, Ali Abokiash, Raouf Kwafi, Issa Abuzied, Iliopsoas Abscess: Presentation, Etiology, Treatment Options, and Outcomes: A Retrospective Analysis of 19 Cases , Al-Mukhtar Journal of Sciences: Vol. 40 No. 1 (2025)
- Jebril S. Elabidi, Asmaa F. Salih, Monia F. Abusarayi, Epidemiological and Clinical Characteristics of Pediatric Urinary Tract Infections in Benghazi, Libya: A Two-Year Retrospective Study , Al-Mukhtar Journal of Sciences: Vol. 40 No. 1 (2025)
- Mohamed A. Alshalwi, Mariam M. Madany, Amal A. Abuseif , Hanan I. El Megasbi, Hamida Taboli, Naema I. Goobaa, Early Postoperative Complete Heart Block after Congenital Heart Disease Surgery: A Two Centre Study in Benghazi , Al-Mukhtar Journal of Sciences: Vol. 39 No. 3 (2024)
You may also start an advanced similarity search for this article.









