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Clinical manifestations of gastro esophageal reflux among patients with chronic laryngitis in Benghazi, 2018

Authors
  • Yosef Hassan. S. Abdulkarim

    Otolaryngology medical col-lage Benghazi university, ENT department, Benghazi medical center
    Author
  • Hajer M. M Farkash

    Otolaryngology medical col-lage Benghazi university, ENT department, Benghazi medical center
    Author
  • Khaled G Hasen

    Otolaryngology department, medical college, Al-Mukhtar university, ENT department, Albeda Hospital
    Author
Keywords:
Gastroesophageal reflux disease, chronic laryngitis, hoarseness of voice
Abstract

Gastroesophageal reflux disease is a chronic, complex condition that may present with atypical symptoms, including  laryngitis. The aim of study to demonstrates the relationship of sings of reflux laryngitis in patients with typical manifestations of Gastroesophageal reflux disease (GERD). The present study included a total of 60 patients suffering chronic laryngitis with a range of age of 23 to 88 years in descriptive study in Benghazi Medical Center in the year 2018. History was collected and indirect laryngoscopy done for cases and data were analyzed using SPSS 23.0. Results The most common symptoms were hoarseness of voice, throat clearing, dysphagia, throat discomfort and globus sensation. No significant association of symptoms with gender of the patients. Most common laryngeal findings were hyperemia, vocal cord changes and posterior commisure hypertrophy. Significant association included only posterior commissure hypertrophy and infra-glottal edema. Conclusions and recommendations, Many didn't seek medical advice and most had no diagnostic procedure. Stronger study designs using proper diagnostic technique and patient education with staff training are recommended.

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References

Alharethy S, Baqays A, Mesallam T, Syouri F, Al Wedami M, Aldrees T, and AlQabbani A. (2018). Correlation between Allergic Rhinitis and LaryngopharyngealReflux BioMed ResearchInternational https://doi.org/10.1155/2018/2951928.

Cobzeanu MD, Voineag M,Drug VL,Ciubotaru A,Cobzeanu BM, Palade OD.(2012). Laryngeal morphological changes due to gastroesophageal reflux disease. Rev Med Chir Soc Med Nat Iasi. 116(4), pp.1011-1015.

De Bortoli N, Nacci A, Savarino E, Martinucci I, Bellini M, Fattori B, Ceccarelli L, Costa F, Mumolo MG, Ricchiuti A, Savarino V, Berrettini S and Marchi S. (2012). How many cases of laryngopharyngeal reflux suspected by laryngoscopy are gastroesophageal reflux disease-related? World J Gastroenterology 18(32), pp. 4363-4370.

Dilen da Silva C, Niedermeier B and Portinho F. (2015). Reflux Laryngitis: Correlation between the Symptoms Findings and Indirect Laryngoscopy. Int Arch Otorhinolaryngol. 19, pp. 234–237.

Dymek A, Dymek L, Starczewska-Dymek L, Bożek A, Dymek T and Nowak K. (2012). Laryngopharyngeal Reflux (LPR) in patients with persistent hoarseness. Otolaryngol Pol. 66(1), pp. 33-8.

El-Serag HB, Sweet S, Winchester CC, Dent J. (2013). Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut. 63(6), pp. 871–880. doi:10.1136/gutjnl-2012-304269.

Heidelbaugh J, Gill A, Harrison R, and Nostrant T. (2008). Atypical Presentations of Gastroesophageal Reflux Disease. Am Fam Physician. 78(4), pp. 483-488.

Koufman J. (1991). The otolaryngologic manifestations of gastroesophageal reflux disease (GERD): A clinical investigation of 225 patients using ambulatory 24-hour ph monitoring and an experimental investigation of the role of acid and pepsin in the development of laryngeal injury, The Laryngoscope. vol. 101, pp. 1–78.

Koufman, J, Aviv J, Casiano R, and Shaw G. (2002). Laryngopharyngeal reflux: a position statement of the committee on speech, voice, and swallowing disorders of the American Academy of Otolaryngology-head and neck surgery. Otolaryngology-Head and Neck Surgery, vol. 127, pp. 32– 35.

Parsons P. and Mastronarde G. (2010). Gastroesophageal reflux disease and asthma, Current opinion in pulmonary medicine, vol.16, no 1, pp 60-63.

Pribuisiene R, Uloza V,andJonaitis L. (2002). Typical and atypical symptoms of laryngopharyngeal reflux disease. Medicina (Kaunas), vol. 38 (7), pp. 699–705.

Reiter R, Hoffmann TK, Pickhard A, Brosch S (2015). Hoarseness—causes and treatments. Dtsch Arztebl Int 112, pp. 329–337.

Yazici Z, Sayin I, Kayhan F, and Biskin S. (2010). Laryngopharyngeal reflux might play a role on chronic nonspecific pharyngitis, European Archives of Oto-Rhino- Laryngology. 267 (4), pp. 571–574.

Yuksel ES and Vaezi MF. (2012). New Developments in Extraesophageal Reflux Disease Gastroenterology & Hepatology.8(9), pp.256-261.

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Published
2025-09-18
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Copyright (c) 2024 Yosef Hassan. S. Abdulkarim, Hajer M. M Farkash, Khaled G Hasen (Author)

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How to Cite

Hassan. S. Abdulkarim, Y. . ., Farkash, H. . M. M. ., & Hasen, K. G. . (2025). Clinical manifestations of gastro esophageal reflux among patients with chronic laryngitis in Benghazi, 2018. Al-Mukhtar Journal of Sciences, 39(1), 20-27. https://doi.org/10.54172/g62ecx82

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