Histological studies on the development of Rat's liver After Birth

• Ebtesam M. M. Gheth

  Zoology Department, Faculty of Science, Omar Al-Mukhtar University, Libya.

  Author

• Abdusalam M. Aboalhaj

  Zoology Department, Faculty of Science, Omar Al-Mukhtar University, Libya.

  Author

• Saad M. S. El-Gharbawy

  Faculty of Veterinary Medicine/ Omar El-Mukhtar University

  Author

• Ibrahim S.H. El-Durssi

  Zoology Department, Faculty of Science, Omar Al-Mukhtar University, Libya.

  Author

In this study, the development of the rat's liver was investigated after birth. using livers of 39  rats with ages from one day after birth to four months.

The cells surround the central veins is not completely arranged and did not take  their regular manner of arrangement till the 10^th day after birth.

At 10days of postnatal life the hepatic parenchyma was represented by regular hepatic cords some of them formed from one cell layer and the others were two cell layers thickness. These cords appeared in the form of radiating coulmns from the central veins. At 4 days of postnatal life the hepatic sinusoids became lined by Von kupffer cells beside the endothelial cells and at the 10^th day after birth the hepatic sinusoids appeared more regular, extending between the hepatic cords and connected with the central veins. after birth the haemopiotic cells decreased in number and distribution.

At age of 10 day after birth the hepatic lobules where clear containing central vein at the center and several portal areas at their angles.

 The capsule become more and more thick and the elastic fibers begin to appear in it at 10 day in postnatal life.

After birth, reticular fibers increased in thickness and distribution, and collagen fibers appeared at the age of 10 days in the portal areas.

غايتون ، أ. س. و هول, ج. ي. (1997) . المرجع في الفسيولوجيا الطبية . ترجمة الدكتور صادق الهلالي . الطبعة التاسعة . منظمة الصحة العالمية . مكتب الشرق الأوسط .

موفق شريف جنيد . (1996) . علم النسج (الجزء النظري) . الطبعة الأولى . منشورات جامعة عمر المختار .

Anwar, M. E., Hamid, S. H., El-Sayed, E. H. and Zohyd, A. S. E. (1989). A histological study of the postnatal development of the liver of albino rat. Egypt. J. Histol. 12(1): 3-11.

Bancroft, J. D. and Gamble, M. (2002). Theory and practice of histological techniques. Fifth ed. Churchill Livingston. Edinburgh, London and New York.

Beams, H. W. and King, R. L. (1942). The origin of Binucleated and mononucleated cells in the liver of rat. Anat. Rec. 93: 281-297.

Crossmon, G. (1937). A modification of Mallory connective tissue stain with discussion of the principle involved. Ant. Rec. 69: 33-38.

Daems, W. T. H. (1961). The micro-anatomy of the smallest Biliary pathways in mouse liver tissue. Acta Anat., 46 (1-2): 1-24.

Deane, H. W. (1944). A cytological study of storage and secretion in the developing liver of the mouse. Anat. Rec., 88: 161-174.

Du Bios, A. M. (1963). "The embryonic liver, in Rouiller". The liver,Vol. 1, P: 1-39. Academic Press, New York.

Elias, H. (1949). A re-examination of the structure of the mammalian liver I. parenchymal architecture. Amer. J. Anat., 84: 331.

El-Keshawy, A. H., Awad, A., Abbass, A. and Moustafa, I. A. (1985). Postnatal changes of the liver of female balady rabbitrs in relation of pregnancy and lactation. Zagazig Vet.. J., 12 (2): 360-390.

Le Bouton, A. V. (1974). Growth, mitosis and morphogenesis of the simple liver acinus in neonatal rat. Develop. Biolo. 41: 22-30.

Lesson, C. R. and Cutts, J. H. (1972). The postnatal development of the rabbit liver. Biolo. Of the Neonate. 20: 404-413.

McKellar, M. (1949). The postnatal growth and mitotic Activity of the liver of albino rat. Am. J. Anat. 85: 263-295.

Moustafa, M. N. K. and Ahmed, M. G. (1995). Early development of the liver in dog. Egypt. J. Anat. 18 (1): 35-53.

Sarrut, S. and Nezeloof, C. (1959). La maturation hepatique. Ses aspects histologues. Rev. Int. Hepat. 9: 425-571. Referred to be Leeson, C. R. and Cutts, J. H. (1972).

St Aubin, P. M. G. and Bucher, N. L. R. (1952). A study of binucleate cell counts in resting and regenerating rat liver employing a mechanical method for the separation of liver cells. Anat. Rec. 112: 797-810.

Sulkin, N. M. (1943). Study of the nucleus in the normal and hyperplastic liver of the rat. Am. J. Anat. 73: 107-125.

• PDF

Copyright (c) 2022 Ebtesam Gheth

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Copyright of the articles Published by Almukhtar Journal of Science (MJSc) is retained by the author(s), who grant MJSc a license to publish the article. Authors also grant any third party the right to use the article freely as long as its integrity is maintained and its original authors and cite MJSc as the original publisher. Also, they accept the article remains published by the MJSc website (except in the occasion of a retraction of the article).