Effect of Human Growth Hormone on Blood Picture in Male Rabbits

Areej A. Mohammed; Ameerah T. Ramadhan; Eman S. Rasheed; Abdalsalam M. A. Bolhaj; Somya A. Aregeb; Aeshah F. Bunaamah; Mohammed El. Mabrok

doi:10.54172/ntrqnw76

Authors

Areej A. Mohammed Zoology Department, Faculty of Science, Omar Al-Mukhtar University, El- Bayda Libya Author
Ameerah T. Ramadhan Zoology Department, Faculty of Science, Omar Al-Mukhtar University Author
Eman S. Rasheed Zoology Department, Faculty of Science, Omar Al-Mukhtar University Author
Abdalsalam M. A. Bolhaj Zoology Department, Faculty of Science, Omar Al-Mukhtar University Author
Somya A. Aregeb Zoology Department, Faculty of Science, Omar Al-Mukhtar University Author
Aeshah F. Bunaamah Zoology Department, Faculty of Science, Omar Al-Mukhtar University Author
Mohammed El. Mabrok Zoology Department, Faculty of Science, Omar Al-Mukhtar University Author

DOI:

https://doi.org/10.54172/ntrqnw76

Keywords:

Human Growth Hormone, Complete Blood Picture, Male Rabbits

Abstract

There has been in recent years an increase in the use of growth hormone (GH) by different people for sports enhancement and for looking and feeling good. However, there are few studies on animals to test the side effects of using growth hormone, especially with high doses for purposes other than medical. Therefore, this study was aimed to investigate the effect of two different high doses of recombinant human growth hormone (rhGH) on some blood pictures in male rabbits. Fifteen (15) white New Zeeland male rabbits were divided randomly into 3 groups: a control group, a low-dose group, and a high-dose group. Rabbits were injected subcutaneously 3 times a week for 6 weeks. After the end of the treatment period, rabbits were sacrificed, and blood samples were collected and analyzed. Injection of the hormone resulted in an increase in the level of GH in the sera of the treated animals. With regard to the blood picture results, the hormone caused a significant increase in the red blood cell count, the concentration of hemoglobin, percent hematocrit, white blood cells, and the platelets; but had no significant effect on the mean corpuscular volume, mean corpuscular hemoglobin and the mean corpuscular hemoglobin concentration.

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