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Experimental Studies on the effects of chlorpyrifos on Rats III. Haematological Findings

Authors
  • Ibrahim S. H. El-durssi

    Zoology Department / College of science / Omar El-Mukhtar University, P.O. Box. 919.
    Author
  • Ifdial O.S. El-Awami

    College of agriculture / Omar El-Mukhtar University, P.O. Box. 919.
    Author
  • Ghyath S. Mahmoud

    College of veterinary medicine, Omar El-Mukhtar University, P.O. Box. 919
    Author
  • Fahim A. Benkhaial

    Food technology department /college of agriculture / Omar El-Mukhtar University, P.O. Box. 919.
    Author
Abstract

This Study performed to investigate the effects of Chlorpyrifos (one of the most used insecticides) on blood pictures of rats.

Thus a total of 110 male rats were used and experiment ally divided into four groups: the first group was used as control group .While the second group of rats received an oral daily doses of 1/10 LD50. The third and fourth groups of rats were administered single oral dose of 1/10 LD50 and 1/30 LD50 respectively .The median lethal dose was determined which appeared to be equal to 81.2 mg/ kg. B. W.

Haematological investigations revealed an increase in white blood cell’s count (WBC), red blood cell’s count (RBC), and mean carpuscular volume (MCV). On the other hand there is a decrase in haemoglobin estimation (Hb), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC)and the total blood platelets count (PLT).

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References

إبراهيم حسين سالم الدرسي ، (2005) . التغيرات المرضية والنسيجية الكيماوية الناتجة عن تجريع مبيد الكلوربايروفوس (الدورسبان) في الجرذان . رسالة ماجستير – قسم علم الحيوان – كلية العلوم – جامعة عمر

المختار .

Chevielle, R.S. (1982). Cell Pathology Lea & febiger.

ترجمة : غياث صالح محمود (1987) الطبعة

الأولى ، مطبعة جامعة الموصل ، الموصل . العراق . رقم الإيداع في المكتبة الوطنية ببغداد 623 لسنة (1987) .

Coles, D.V.M & Embert, H. (1986). Veterinary Clinical Pathology. 4th ed. W.B. Saunders Company.

El-Gendy. K, Ali. N., (1999). Biochemical Targets Effected by Sublethal doses of cypermethrin in mice . Egypt . J. Agric .Res. 77(2): 701-711.

El-Sawak, A. A., Hussein, Y. A. and El-Manakhly, E. M. (1992). Histopathological changes in rats intoxicated with organophosphorus insecticide “Leptophos”. Egypt. J. Comp. Path. Clin. Path.5 (1): 137-149.

Marzouk, S. and El- Gendy , K.(1997). Some biological effects of the insecticide carbaryl on mice Bull, Alex. Fac. Med. Vol. 33 (1): 87-92.

Matsushima, Y., Uchide, D., Saitoh, M., Kamasaki, Y., Isama , K., Kanirua, M., Inoue, T. and Kanno, J. (2003). Twenty–eight day repeated dose oral toxicity test of synergist of a pyrethroid insecticide, 2, 3, 3, 3, 2, 3, 3, 3- Octachlorodi propyl ether (S-42) in rats, Kokuritsu lyakuhin shokuhin Eisei kenkynusho Hokoku. 121: 40–47.

Yousef, M.I., El-Demerdash, F.M. Kamel, K. I. and Al –Salhen, K.S. (2003). Changes in some hematological and biochemical indices of rabbits induced by Isoflavones and cypermethrin. Toxicol. 189: 223-234.

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Published
2007-04-30
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How to Cite

El-durssi, I. S. H., El-Awami, I. O. ., Mahmoud, G. S., & Benkhaial, F. A. . (2007). Experimental Studies on the effects of chlorpyrifos on Rats III. Haematological Findings. Al-Mukhtar Journal of Sciences, 14(1), 147-156. https://doi.org/10.54172/mjsc.v14i1.885