Epidemiological surveillance Profile Of Cancer In Eastern Benghazi ,Libya 2021
DOI:
https://doi.org/10.54172/g24zbz23Keywords:
Eastern Libya, Benghazi region, Oncology Department, Tobruk Medical CenterAbstract
Cancer remains a major public health concern globally and is the second leading cause of death in Libya. Despite its growing burden, comprehensive data on cancer incidence in eastern Libya remains limited. This study aims to estimate the incidence and distribution of cancer types in the eastern region of Benghazi, Libya, and compare findings with regional and global data to support health planning, training, and research efforts. A retrospective observational surveillance study was conducted using data from oncology departments at Tobruk Medical Center and Al-Bayda Hospital. All cancer cases diagnosed and registered from January 1 to December 31, 2021, were included. A total of 398 confirmed cases were analyzed by sex, type, and frequency. Statistical analysis was performed using IBM SPSS v26 with chi-square tests applied for gender related differences. The overall incidence was 61.23 cases per 100,000 population. Females constituted 58.5% of cases, with breast cancer being the most prevalent (24.1%), followed by colon (9%), uterine (8.2%), and lung cancers (7.78%). Male patients were more affected by colon, lung, and prostate cancers. Hematological malignancies and rare cancers were also observed, with statistically significant gender-based differences (p < 0.001). Comparisons with data from Misurata and global estimates revealed similar trends for certain cancers but also notable local variations, particularly in colon and esophageal cancer rates. This study provides critical epidemiological insight into cancer incidence in eastern Libya. The findings highlight the need for sex-specific cancer strategies and reinforce the importance of establishing a comprehensive national cancer registry for improved disease surveillance and healthcare planning.
References
Abu Fekirin, I. H. (2015). Population change in Al-Bayda City, Libya during the period (1987–2015) using geographical information system [Unpublished manuscript/Report].
Arzanova E , Harvey N. Mayrovitz , (2022), the epidemiology of breast cancer , http://www.ncbi.nlm.gov/books/NBK583819/ doi: 10.36255/exon –publication –breast – cancer-epidemiology .
Aslani ,A , .M orsali, S, et al ( 2024)Adult hodgkin lymphoma incidence trends in the United states from 2000 to 2020 , http: // doi.org/ 10.1038/ s41598-02469975-3.
Bodalal, Z., Azzuz, R., Bendardaf, R. (2014). Cancers in Eastern Libya: First results from Bengha-zi Medical Center. World Journal of Gastroenterology, 20(20), 6293–6301. https://doi.org/10.3748/wjg.v20.i20.6293
Bray, F., Laversanne, M., Sung, H., Ferlay, J., Siegel, R. L., Soerjomataram, I., & Jemal, A. (2024). Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality world-wide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 74(3), 229–263. https://doi.org/10.3322/caac.21790
Bureau of Statistics and Census. (2021). Total population of Libya. Libyan Government.
Cameron J, Annie P. Im , et al (2025 ), Marrow microenvironmental pathobiology and therapeutic opportunities for TP 53 – mutated myleodysplastic syndrome / acute myeloid , cancer2026 18(2), 275 http: //doi.org/ 10.3390/cancers 18020275.
Condoiu , C, Baloi , A, et al ( 2026). Clinically significant ISUP upgrading in the multi paramet-ric MRI. biopsy burden outperforms complex machine learning models in the single cen-ter exploratory cohort ., cancer 2026 , http://doi.org /10.3390/cancers 18050730.
Grimes, D. A., & Schulz, K. F. (2002). Descriptive studies: What they can and cannot do. The Lan-cet, 359(9301), 145–149. https://doi.org/10.1016/S0140-6736(02)07373-7
Huang J , Chan SC , lok v, zhang L , lucero-prisno DE 3rd , Xu W , et al (2024) , global burden , risk factor , and trend s of non Hodgkin lymphoma , A worldwide analysis of cancer regis-tries. Doi: 10.1002/cam4.7056. PMID: 38477498.
IBM Corp. (2019). IBM SPSS Statistics for Windows (Version 26.0). IBM Corp.
International Agency for Research on Cancer (IARC). (2020). GLOBOCAN 2020: Cancer to-day. https://gco.iarc.fr/today
Ismail, F., Elsayed, A. G., Eshaibani, S., Elhuni, S., & Eltaher, F. (2021). Cancer incidence in the Tobruk area, eastern Libya: First results from Tobruk Medical Centre. Epidemiology and Health, 43, e2021050. https://doi.org/10.4178/epih.e2021050
Kim,J, Harper, A,McCormack,V et al .(2025)Global patterns and trends in breast cancer incidence and mortality across 185 countries ,med 31,1154-1162, https://doi.org/10.1038/s41591-025-03502-3.
Lakovos A , Marine D , et al (2026).classification of pancreatic cancer and normal tissue in 2D and 3 D optical coherence tomography image using convolutional neural networks: Acomparative study , http : // doi.org/ 10.3390/cancers 18050732.
Ophira G, cheng-Haryip et al (2020), breast cancer early detection : a phased approach to imple-mentation ,doi : 10.1002/cncr .32887
Ouassma M.N. (2025)guidelines for the early detection and screening of the breast cancer . ISSN :1020-0428 .
Qi Li , Hanyu Wang, Ze Chen , Jiahui Xiang , Yong Huang et al (2024) , Global , regional , and na-tional epidemiology of nasopharyngeal carcinoma in middle aged and elderly patients from 1990 t0 2021., http;//doi.org/10.1016/j.arr.2024.102613.
Rojas GA, Hubbard AK, Diessner BJ , Ribeirro KB , et al (2021) . international trends in inci-dence of osteosarcoma INT J Cancer 2021. Doi : 10.1002/ijc .33673. PMID 33963769.
Sakari J , Tuomo k , et al (2022) , genetic risk factors have a substantial impact on healthy life style, doi :10.1038/s41591-022-01957-2
Sergiusz L , Marcin C , Alicja forma , et al (2021) . Breast cancer – epidemiology ,Risk factor , classification, prognostic markers , and current treatment strategies
Siegel, R. L., Miller, K. D., Fuchs, H. E., & Jemal, A. (2021). Cancer statistics, 2021. CA: A Can-cer Journal for Clinicians, 71(1), 7–33. https://doi.org/10.3322/caac.21654
Smolarz, B , . lukasiewicz,H, ; Samulak, D : piekarska,E, et al (2025) lung – cancer –Epidemiology , pathogenesis , treatment and Molecular Aspect .int.J.MOI, Sci , 2025, http://doi.org/10.3390/ijms26052049.
Sung, H., Ferlay, J., Siegel, R. L., Laversanne, M., Soerjomataram, I., Jemal, A., & Bray, F. (2021). Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality world-wide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 71(3), 209–249. https://doi.org/10.3322/caac.21660
Sung H, Siegel, R. L M et al (2024), colorectal cancer incidence trends in younger versus older adults : an analysis of population – based cancer registry data 2024, 26,51-63.
S.shiovitz , L.A.korde (2014), Genetic of breast cancer : atopic in evolution, doi:10.1093/annonc/mdv022 .
Thomas A.sellers (2023), genetic factors in the pathogenesis of breast cancer :their role and rela-tive importance http://doi.org /10.1093/jn/127.5.929s
Wenji guo , James .L.Li (2025), genetic and nongenetic risk factors for breast cancer risk estima-tion , doi : 10.1001/jamanetworkopen.2025. 5804
World Health Organization (WHO). (2022). Cancer. https://www.who.int/news-room/fact-sheets/detail/cancer
Wu, Z., Xia, F., & Lin, R. (2024). Global burden of cancer and associated risk factors in 204 coun-tries and territories, 1980–2021: A systematic analysis for the GBD 2021. Journal of He-matology & Oncology, 17, 119. https://doi.org/10.1186/s13045-024-01640-8
Zarmouh, A., Elma, A., Elhadi, M., Abodina, A., & Alshibani, A. (2021). Cancer incidence in the middle region of Libya: Data from the cancer epidemiology study in Misurata. Cancer Re-ports, 4(6), e1448. https://doi.org/10.1002/cnr2.1448
Zhang, X., Yang, L., Liu, S., Cao, L. L., Wang, N., Li, H. C., & Ji, J. F. (2024). Interpretation on the report of global cancer statistics 2022. Chinese Journal of Oncology, 46(7), 710-721. https://doi.org/10.3760/cma.j.cn112152-20240416-00152
Zhang Y, Rumgay H, Li m , Yu H, Pan H, Ni J. ( 2024)The global landscape of bladder cancer inci-dence and mortality. doi: 10.7189 /jogh .13. 04109. PMID: 37712386.
Downloads
Published
Issue
Section
License
Copyright (c) 2026 Rudhuway Abdulqadir Mtawil, Fahd Abdulaziz Abid, Aml Abdulqadir Mtawil, Aliyah Husayn Mohammed (Author)

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Copyright of the articles Published by Almukhtar Journal of Science (MJSc) is retained by the author(s), who grant MJSc a license to publish the article. Authors also grant any third party the right to use the article freely as long as its integrity is maintained and its original authors and cite MJSc as the original publisher. Also, they accept the article remains published by the MJSc website (except in the occasion of a retraction of the article).










