Synthesis of Pyrazolopyrazol Derivative via Reactions of Donor Compounds with 4-(2-Hydroxybenzylidene)-3-methyl-1H-pyrazol-5(4H)-one

• Ashraf H. Abou-Zied

  Chemistry Department, Faculty of science, Omar Al-Mukhtar University, Al-Beida, Libya

  Author

• Salema A. A. El-Mansory

  Chemistry Department, Faculty of science, Omar Al-Mukhtar University, Al-Beida, Libya

  Author

4-(2-hydroxybenzylidene)-3-methyl-1H-pyrazol-5(4H)-one  3 reacted with hydrazine, phenylhydrazine, semicarbazide, thiosemicarbazide, acylthiosemicarbazide and acetylthiosemicarbazide as donor compounds in ethanol in presence of acetic acid or sulphuric acid by reflux to form pyrazolopyrazole derivative s  4 to 9, Respectively. These products which have been characterized by FT-IR, ¹H-NMR, ¹³C-NMR, mass spectra and elemental analysis have been produced in good yields.

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