Clinical and Hematological Effects of Ketamine alone and Ketamine-Acepromazine in Combination in Local Breed Dogs

Authors

  • Faraj. A. Bin Hukoumih Department of Surgery & Reproductive, Faculty of Veterinary Medicine, Azzaytuna University, Tarhouna, Libya Author
  • Khaled M. A. Husin Department of Surgery & Reproductive, Faculty of Veterinary Medicine, Omar Al- Mukhtar University, Al-Bayda, Libya Author
  • Abdulmutalib Hammad Ali Department of Environment Sciences, Faculty of Natural Resources Environment Sciences, Omar Al- Mukhtar University, Al-Bayda, Libya Author
  • Salha E. Embreauk Department of Surgery & Reproductive, Faculty of Veterinary Medicine, Omar Al- Mukhtar University, Al-Bayda, Libya Author

DOI:

https://doi.org/10.54172/sw5ew296

Keywords:

Acepromazine, Ketamine, Corneal Reflex, Pedal Reflex and Palpebral reflex

Abstract

To select the best general anesthetic mixture for use during surgical procedures on the local breed of dogs in Al-Bayda, Libya, an experimental study was carried out to compare the effects of ketamine alone and in combination with acepromazine on anesthetic parameters, on physiological and hematological parameters. Twenty dogs of a local breed were used in the experimental investigation, and they were randomly divided into 2 groups of ten dogs each. Using physical recording and laboratory analysis, information was gathered to examine the physiological consequences of anesthetic combinations, including anesthetic effects and hematological effects. According to the study's findings, acepromazine and ketamine together resulted in a general anaesthetic duration of (55.50 ± 7.849) min and an animal recovery time of (72.8 ± 10.454) min, whereas ketamine alone produced a general anesthetic duration of (29.50 ± 5.986) min.The result also showed that the physiological and hematological parameters remained significantly unchanged during the anesthesia in both groups. Since acepromazine and ketamine have a longer duration of action on the dog brain than other anesthetic combinations, they were a good choice for surgical procedures on local breed dogs. 

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Published

2026-06-24

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How to Cite

Clinical and Hematological Effects of Ketamine alone and Ketamine-Acepromazine in Combination in Local Breed Dogs. (2026). Al-Mukhtar Journal of Basic Sciences, 18(1), 118-135. https://doi.org/10.54172/sw5ew296