Synthesis, Spectroscopy, and Biological Activity of Uranium (IV) Complex with 8-Hydroxyquinoline and Guanidine

Hassan Aberrwaila; Khaled Muftah Elsherif; Abdul-Aziz Suliman Aburowais

doi:10.54172/m1q0n493

Authors

Hassan Aberrwaila Chemistry Department, Faculty of Science, Misurata University, Misurata, Libya Author
Khaled Muftah Elsherif Libyan Authority for Scientific Research, Tripoli, Libya Author
Abdul-Aziz Suliman Aburowais Department of Food Industries, Faculty of Agriculture, Misurata University Author

DOI:

https://doi.org/10.54172/m1q0n493

Keywords:

Uranium, 8-hydroxyquinolne, Guanidine, Spectroscopic investigation

Abstract

A mixed ligand complex of uranium (IV) synthesized from 8-hydroxyquinoline (8-HQ) and guanidine (G) was prepared and studied using infrared spectroscopy (FT-IR) and electronic spectroscopy (UV-VIS). The complex was formed by reacting an equimolar proportion of uranium acetate with 8-HQ and guanidine. The complex's FT-IR data show that the complex is formed via deprotonation of the hydroxyl group of the HQ ligand. Similarly, a positive shift in the vibrational mode of mixed ligand complexes at around 3650 cm^-1 confirms their coordination via nitrogen donor’s HQ and G. The electronic spectrum of uranium complex showed absorption at around 350 nm due to charge transfer transition, which is responsible for the complex's intense orange colour, and it is obvious proof of metal ion coordination with nitrogen and oxygen atoms on the two ligands. Using the well diffusion technique, the produced complex was tested using four strains of various bacteria (Staphylococcus aureus, Escherichia coli, Klebsiella spp., and pseudomonas spp.). The complex was more effective against Gram-positive bacteria S. aureus and Gram-negative bacteria Klebsiella spp.

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